GeneNet Engine is provided by the Feltus Lab at Clemson University, with site hosting graciously provided by the Clemson University Genomics Institute (CUGI). This database is an exploratory tool to aid hypothesis and biomarker development at a systems-level for genotype-phenotype relationships.
Expressed phenotypes may arise due to interactions between multiple genes in a system and effects from the surrounding environment. Therefore, a high systems-level view is needed to identify gene sets causal for a trait. The ability to predict genes that effect important traits is of great importance to agriculture and health. Systems genetic approaches, that combine genomics, gene co-expression networks and data from genetic studies help provide a view at the systems-level of gene interactions. Because co-expressed genes tend to be involved in similar processes, it is expected that co-expressed genes may work together to give rise to specific pheontypes.
The network module serves as the basic unit of exploration in this site.
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